MSDS Name: Fluorescein,
Disodium Salt
Catalog Numbers:
AC173240000, AC173241000,
AC173245000
Synonyms:
Water Soluable Fluorescein;
Resorcinol Phthalein Sodium; Acid Yellow
73
Company Identification (Europe): Acros
Organics BVBA
Janssen Pharmaceuticalaan 3a
2440 Geel, Belgium
Company Identification (USA):
Acros Organics
One Reagent Lane
Fairlawn, NJ 07410
For information in North America, call:
800-ACROS-01
For information in Europe, call:
0032(0) 14575211
For emergencies in the US, call CHEMTREC:
800-424-9300
For emergencies in Europe, call:
0032(0) 14575299
**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS#
|
Chemical Name |
% | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 518-47-8 |Fluorescein,
Disodium Salt
| 100 | 208-253-0 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: None Listed.
Risk Phrases: None Listed.
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Appearance: orange to red.
Caution! Hygroscopic. May cause eye and skin
irritation. May cause
respiratory and digestive tract irritation.
Target Organs: Kidneys.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
In
high doses may cause gastric irritation, nausea, vomiting, fever,
skin rashes, and blood abnormalities including anemia.
Inhalation:
Inhalation of dust may cause respiratory tract irritation.
Chronic:
Not available.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. If irritation
develops, get medical aid.
Skin:
Flush skin with plenty of soap and water for at least 15 minutes
while removing contaminated clothing and shoes. Get medical aid if
irritation develops or persists.
Ingestion:
If
victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical
aid if irritation or symptoms occur.
Inhalation:
Remove from exposure to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen.
Get medical aid if cough or other symptoms appear.
Notes to Physician:
Treat symptomatically and supportively.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As
in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Autoignition Temperature:Not
available.
Flash Point:
Not available.
Explosion Limits, lower:Not
available.
Explosion Limits, upper:Not
available.
NFPA Rating:
Not published.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use
proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Avoid generating dusty conditions.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Use only in a well-ventilated area.
Minimize dust generation and accumulation. Avoid contact with eyes,
skin, and clothing. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
+--------------------+-------------------+-------------------+-----------------+
| Chemical Name |
ACGIH | NIOSH
|OSHA - Final PELs|
|--------------------|-------------------|-------------------|-----------------|
| Fluorescein,
Disodi|none listed |none listed
|none listed |
| um Salt
|
|
|
|
+--------------------+-------------------+-------------------+-----------------+
OSHA Vacated PELs:
Fluorescein,
Disodium Salt:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29CFR
1910.134 or European Standard EN 149. Always use a
NIOSH or European Standard EN 149 approved respirator
when necessary.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State:
Powder
Appearance:
orange to red
Odor:
Not available.
pH:
Not available.
Vapor Pressure:
Not available.
Vapor Density:
Not available.
Evaporation Rate:
Not available.
Viscosity:
Not available.
Boiling Point:
Not available.
Freezing/Melting Point:
314-316 deg C
Decomposition Temperature:
Solubility in water:
Soluble.
Specific Gravity/Density:
Molecular Formula:
C20H10Na2O5
Molecular Weight:
376.0466
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Moisture.
Incompatibilities with Other
Materials:
Strong oxidizing agents.
Hazardous Decomposition
Products:
Carbon monoxide, carbon dioxide, sodium oxide.
Hazardous Polymerization: Has
not been reported
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 518-47-8: LM5425000
LD50/LC50:
CAS# 518-47-8: Oral, mouse: LD50 = 4738 mg/kg; Oral, rat: LD50 =
6721 mg/kg.
Carcinogenicity:
Fluorescein,
Disodium Salt -
Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology:
No
data available.
Teratogenicity:
No
data available.
Reproductive Effects:
No
data available.
Neurotoxicity:
No
data available.
Mutagenicity:
No
data available.
Other Studies:
No
data available.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Chemical waste generators must determine whether
a discarded chemical
is classified as a hazardous waste.
US EPA guidelines for the classification
determination are listed in
40 CFR Parts 261.3. Additionally, waste generators
must consult state
and local hazardous waste regulations to ensure
complete and accurate
classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
**** SECTION 14 - TRANSPORT INFORMATION ****
US DOT
No
information available
Canadian TDG
No
information available.
**** SECTION 15 - REGULATORY INFORMATION ****
US FEDERAL
TSCA
CAS# 518-47-8 is listed on the TSCA inventory.
Health &
Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test
Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA
Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
Section 302 (RQ)
None of the chemicals in this material have an RQ.
Section 302 (TPQ)
None of the chemicals in this product have a TPQ.
Section 313
No
chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous
Substances under the CWA.
None of the chemicals in this product are listed as Priority
Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants
under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous
by
OSHA.
STATE
Fluorescein,
Disodium Salt is not present on state lists from CA, PA,
MN, MA, FL, or NJ.
California No Significant Risk
Level:
None of the chemicals in this
product are listed.
European/International Regulations
European Labeling in Accordance
with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
WGK (Water Danger/Protection)
CAS# 518-47-8: 2
United Kingdom Occupational Exposure Limits
Canada
CAS# 518-47-8 is listed on Canada's DSL List.
This product has a WHMIS classification of C, D2B.
CAS# 518-47-8 is not listed on Canada's Ingredient Disclosure List.
Exposure Limits
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 4/01/1998 Revision #1 Date: 8/02/2000
The information above is
believed to be accurate and represents the best
information currently available
to us. However, we make no warranty of
merchantability or any other
warranty, express or implied, with respect to
such information, and we assume
no liability resulting from its use. Users
should make their own
investigations to determine the suitability of the
information for their particular
purposes. In no way shall the company be
liable for any claims, losses,
or damages of any third party or for lost
profits or any special,
indirect, incidental, consequential or exemplary
damages, howsoever arising, even
if the company has been advised of
the possibility of such damages.