**** SECTION 1 - CHEMICAL PRODUCT AND COMPANY
IDENTIFICATION ****
MSDS Name: 10 % Buffered
Formalin
Catalog Numbers:
SF99 20, SF99 4,
SF9920, SF994
Synonyms:
None.
Company Identification: Fisher
Scientific
1 Reagent Lane
Fairlawn, NJ
07410
For information, call:
201-796-7100
Emergency Number:
201-796-7100
For CHEMTREC assistance, call:
800-424-9300
For International CHEMTREC assistance, call:
703-527-3887
**** SECTION 2 -
COMPOSITION, INFORMATION ON INGREDIENTS
****
+----------------+--------------------------------------+----------+-----------+
|
CAS# |
Chemical Name |
% | EINECS#
|
|----------------|--------------------------------------|----------|-----------|
|
50-00-0 |Formaldehyde
| 3.9-4.0 |
200-001-8
|
|----------------|--------------------------------------|----------|-----------|
|
67-56-1 |Methyl Alcohol
| 2.0 % |
200-659-6
|
|----------------|--------------------------------------|----------|-----------|
|
127-09-3 |Sodium Acetate
| 1.2-2.0 |
204-823-8
|
|----------------|--------------------------------------|----------|-----------|
|
7732-18-5 |Water
| Balance
| 231-791-2
|
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: None Listed.
Risk Phrases: None Listed.
**** SECTION 3 - HAZARDS
IDENTIFICATION ****
EMERGENCY
OVERVIEW
Not available.
Potential Health
Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May cause skin sensitization,
an allergic
reaction, which
becomes evident upon re-exposure to this material.
Ingestion:
Cannot be made
non-poisonous. May cause central nervous system
depression, kidney damage, and liver damage. Causes
gastrointestinal
irritation with
nausea, vomiting and diarrhea.
Inhalation:
Causes respiratory
tract irritation. May cause allergic respiratory
reaction.
Chronic:
May cause cancer
according to animal studies. May cause reproductive
and fetal effects.
**** SECTION 4 - FIRST AID
MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15
minutes,
occasionally lifting the
upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin
with plenty of soap and water for at
least 15 minutes while removing contaminated clothing and
shoes.
Ingestion:
Do NOT induce vomiting. If victim is conscious and alert, give
2-4
cupfuls of milk or water.
Never give anything by mouth to an
unconscious person. Get medical aid.
Inhalation:
Remove from exposure
to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give
oxygen.
Get medical
aid.
Notes to Physician:
**** SECTION 5 - FIRE FIGHTING
MEASURES ****
General
Information:
As in any fire, wear
a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and
full
protective gear. During a
fire, irritating and highly toxic gases
may be generated by thermal decomposition or
combustion.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide,
water spray or
alcohol-resistant
foam. Cool containers with flooding quantities of
water until well after fire is out.
**** SECTION 6 - ACCIDENTAL
RELEASE MEASURES ****
General Information: Use
proper personal protective equipment as indicated
in
Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or
earth),
then place in suitable
container. Clean up spills immediately,
observing precautions in the Protective Equipment
section.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after
handling. Wash hands before eating. Use only
in a well-ventilated area. Do not get in eye>
Engineering Controls:
Use adequate
general or local exhaust ventilation to keep airborne
concentrations below the permissible exposure
limits.
Personal Protective
Equipment
Eyes:
Wear appropriate protective eyeglasses or
chemical
safety goggles as described by OSHA's eye and
face
protection regulations in 29 CFR 1910.133 or
European
Standard EN166.
Skin:
Wear appropriate protective gloves to
prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent
skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in
29CFR
1910.134 or European Standard EN 149. Always use
a
NIOSH or European Standard EN 149 approved
respirator
when necessary.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
****
Physical State:
Liquid
Appearance:
not available
Odor:
none reported
pH:
Not
available.
Vapor Pressure:
Not available.
Vapor Density:
Not available.
Evaporation Rate:
Not available.
Viscosity:
Not available.
Boiling Point:
Not
available.
Freezing/Melting Point: Not
available.
Autoignition Temperature: Not
applicable.
Flash Point:
> 194 deg F (> 90.00 deg C)
Explosion Limits,
lower: Not available.
Explosion Limits, upper:
Not available.
Decomposition Temperature: Not
available.
Solubility:
Soluble in water.
Specific Gravity/Density:
Not available.
Molecular Formula:
Mixture
Molecular Weight:
Not applicable.
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable
under normal temperatures and pressures.
Conditions to
Avoid:
Incompatible materials,
excess heat.
Incompatibilities with Other
Materials:
Strong
oxidants.
Hazardous Decomposition
Products:
Irritating and toxic
gases.
Hazardous Polymerization: Has not been
reported
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 50-00-0:
LP8925000
CAS# 67-56-1:
PC1400000
CAS# 127-09-3:
AJ4300010
CAS# 7732-18-5:
ZC0110000
LD50/LC50:
CAS# 50-00-0: Draize test, rabbit, eye: 750 ug/24H Severe;
Draize
test, rabbit, eye: 750 ug
Severe; Draize test, rabbit, eye: 10 mg
Severe; Draize test, rabbit, skin: 2 mg/24H Severe; Draize
test,
rabbit, skin: 50 mg/24H
Moderate; Inhalation, mouse: LC50 = 454
gm/m3/4H; Inhalation, rat: LC50 = 203 mg/m3; Oral, mouse: LD50 =
42
mg/kg; Oral, rat: LD50 = 100
mg/kg; Skin, rabbit: LD50 = 270 uL/kg.
CAS# 67-56-1: Draize test, rabbit, eye: 40 mg Moderate; Draize
test,
rabbit, eye: 100 mg/24H
Moderate; Draize test, rabbit, skin: 20
mg/24H Moderate; Inhalation, rat: LC50 = 64000 ppm/4H; Oral,
mouse:
LD50 = 7300 mg/kg; Oral,
rabbit: LD50 = 14200 mg/kg; Oral, rat: LD50
= 5628 mg/kg; Skin, rabbit: LD50 = 15800 mg/kg.
CAS# 127-09-3: Draize test, rabbit, eye: 10 mg Mild;
Draize test,
rabbit, skin: 500
mg/24H Mild; Inhalation, rat: LC50 = >30 gm/m3/1H;
Oral, mouse: LD50 = 6891 mg/kg; Oral, rat: LD50 = 3530
mg/kg; Skin,
rabbit: LD50 = >10
gm/kg.
CAS# 7732-18-5: Oral, rat:
LD50 = >90 mL/kg.
Carcinogenicity:
Formaldehyde
-
ACGIH: A2 -
suspected human carcinogen
California: carcinogen; initial date 1/1/88
NIOSH: occupational
carcinogen
NTP: Suspect carcinogen
OSHA: Possible Select carcinogen
IARC: Group 2A carcinogen
Methyl Alcohol -
Not
listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Sodium Acetate -
Not listed by
ACGIH, IARC, NIOSH, NTP, or OSHA.
Water
-
Not listed by ACGIH, IARC,
NIOSH, NTP, or OSHA.
Epidemiology:
No information available.
 sp; Specific Developmental
Abnormalities: craniofacial and
musculoskeletal, ipr-mouse TDLo=240 mg/kg.
Reproductive Effects:
Formaldehyde
effects on Fertility: male index, itt-rat TDLo=400
mg/kg; post- implantation mortality, ims-mouse TDLo=259
mg/kg.
Paternal Effects:
spermatogenesis, orl-rat TDLo=200 mg/kg;
testes/sperm duct/epididymis, ipr-rat TDLo=80 mg/kg.
Neurotoxicity:
No
information available.
Mutagenicity:
Formaldehyde DNA
Damage: human fibroblast 100 umol/L DNA Inhibition:
human cell types 210 umol/L. Unscheduled DNA Synthesis: rat
cell
types 50 umol/L. Gene
Mutation in Mammalian Cells: human lymphocyte
130 umol/L.
Other
Studies:
No data
available.
**** SECTION 12 - ECOLOGICAL INFORMATION
****
Ecotoxicity:
Atlantic salmon LC50=173 uL/L/96H; Catfish (fresh
water)
TLm=32ppm/24H; Flounder
(salt water) TLm=100-330 ppm/48H; Fathead
minnowLC50=10-100 uL/L/96H; Rainbow trout LC50=
168mg/L/48H;
Zebrafish
LC50=41mg/L/96H; Water flea LC50=52 mg/L/24H. Cas# 50-00-0:
LC50(96Hr.) rainbow trout = 0.12 mL/L;
flowthrough
bioassay; LC50(96Hr.)
fathead minnow = 24.1 mg/L; flowthrough
conditions; LC50 (96Hr.) bluegill = 0.10 mg/L;
Flow-through
conditions; EC50
(96Hr.) water flea = 20 mg/L; EC50 (30
min)photobacterium phospherum = 3.00-10.2 mg/L;
Microtox.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of
in a manner consistent with federal, state, and local
regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
US DOT
Shipping Name:
AVIATION REGULATED LIQUID,N.O.S.
(10%
FORMALIN)
Hazard Class:
9
UN Number:
UN3334
Packing
Group:
Canadian TDG
No information available.
**** SECTION 15 - REGULATORY
INFORMATION ****
US FEDERAL
TSCA
CAS# 50-00-0 is listed on the
TSCA inventory.
CAS# 67-56-1 is
listed on the TSCA inventory.
CAS#
127-09-3 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.
This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
CAS# 50-00-0 is listed as a Hazardous Substance under the
CWA.
None of the chemicals in this
product are listed as Priority
Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic
Pollutants
under the
CWA.
OSHA:
CAS# 50-00-0 is considered highly hazardous by
OSHA.
STATE
Formaldehyde can be found on
the following state right to know lists:
California,
New Jersey, Florida, Pennsylvania, Minnesota,
Massachusetts.
Methyl Alcohol can be found on the
following state right to know
lists: California, New
Jersey, Florida, Pennsylvania, Minnesota,
Massachusetts.
Sodium Acetate is not present on state
lists from CA, PA, MN, MA, FL,
or
NJ.
Water is not present on state lists from CA, PA,
MN, MA, FL, or NJ.
The following statement(s) is(are)
made in order to comply with
the California Safe
Drinking Water Act:
WARNING: This product contains
Formaldehyde, a chemical known to the
state of
California to cause cancer.
California No Significant
Risk Level:
CAS# 50-00-0: no significant risk level =
40 ug/day
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
WGK (Water
Danger/Protection)
CAS# 50-00-0:
2
CAS# 67-56-1:
1
CAS# 127-09-3:
1
CAS# 7732-18-5: No information
available.
United Kingdom Occupational Exposure
Limits
CAS# 67-56-1: OES-United
Kingdom, TWA 200 ppm TWA; 266 mg/m3 TWA
CAS# 67-56-1: OES-United Kingdom, STEL 250 ppm STEL; 333 mg/m3
STEL
CAS# 67-56-1: OES-United
Kingdom, STEL 250 ppm STEL; 333 mg/m3 STEL
Canada
CAS# 50-00-0 is listed on
Canada's DSL List.
CAS# 67-56-1 is
listed on Canada's DSL List.
CAS#
127-09-3 is listed on Canada's DSL List.
CAS# 7732-18-5 is listed on Canada's DSL List.
CAS# 50-00-0 is listed on Canada's Ingredient Disclosure
List.
CAS# 67-56-1 is listed on
Canada's Ingredient Disclosure List.
CAS# 127-09-3 is not listed on Canada's Ingredient Disclosure
List.
CAS# 7732-18-5 is not listed
on Canada's Ingredient Disclosure List.
Exposure
Limits
CAS# 50-00-0: OEL-ARAB
Republic of Egypt:TWA 2 ppm (3 mg/m3)
OEL-AUSTRALIA:TWA 1 ppm (1.5 mg/m3);STEL 2 ppm (3
mg/m3);CAR
OEL-BELGIUM:TWA 1 ppm
(1.2 mg/m3);STEL 2 ppm ( OEL-HUNGARY:STEL 0.6 mg/m3;Carcinogen
OEL-JAPAN:TWA 0.5 ppm (0.61
mg/m3);Carcinogen
OEL-THE
NETHERLANDS:TWA 1 ppm (1.5 mg/m3);STEL 2 ppm (3 mg/m3)
OEL-THE PHILIPPINES:TWA 5 ppm (6 mg/m3)
OEL-POLAND:TWA 2 mg/m3
OEL-RUSSIA:TWA 0.5 ppm;STEL 0.5
mg/m3;Skin
OEL-SWEDEN:TWA 0.5 ppm
(0.6 mg/m3);STEL 1 ppm (1. mg/m3)
OEL-SWITZERLAND:TWA 0.5 ppm (0.6 mg/m3);STEL 1 pp (1.2
mg/m3)
OEL-THAILAND:TWA 3 ppm;STEL
5 ppm
OEL-TURKEY:TWA 5 ppm (6
mg/m3)
OEL-UNITED KINGDOM:TWA 2
ppm (2.5 mg/m3);STEL 2 ppm (2.5 mg/m3)
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH
TLV
OEL IN NEW ZEALAND, SINGAPORE,
VIETNAM check ACGI TLV
CAS#
67-56-1: OEL-ARAB Republic of Egypt:TWA 200 ppm (260
mg/m3);Skin
**** SECTION 16 - ADDITIONAL INFORMATION
****
MSDS Creation Date: 7/12/1999
Revision #3 Date: 8/02/2000
The
information above is believed to be accurate and represents the
best
information currently available to us. However,
we make no warranty of
merchantability or any other
warranty, express or implied, with respect to
such
information, and we assume no liability resulting from its use.
Users
should make their own investigations to
determine the suitability of the
information for their
particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for
lost
profits or any special, indirect, incidental,
consequential or exemplary
damages, howsoever arising,
even if the company has been advised of
the
possibility of such
damages.
--------------------------------------------------------------------------------