**** SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION ****
MSDS Name: Acetone, 99+%
Catalog Numbers:
AC177170000, AC177170010, AC177170025, AC177170200, AC177170250
Synonyms:
2-Propanone; Dimethyl ketone.
Company Identification (Europe): Acros Organics BVBA
Janssen Pharmaceuticalaan 3a
2440 Geel, Belgium
Company Identification (USA): Acros Organics
One Reagent Lane
Fairlawn, NJ 07410
For information in North America, call: 800-ACROS-01
For information in Europe, call: 0032(0) 14575211
For emergencies in the US, call CHEMTREC: 800-424-9300
For emergencies in Europe, call: 0032(0) 14575299
**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 67-64-1 |Acetone | >99 | 200-662-2 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: XI F
Risk Phrases: 11 36 66 67
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Highly flammable. Irritating to eyes. Repeated exposure may cause
skin dryness or cracking. Vapors may cause drowsiness and dizziness.
Potential Health Effects
Eye:
Produces irritation, characterized by a burning sensation, redness,
tearing, inflammation, and possible corneal injury.
Skin:
Exposure may cause irritation characterized by redness, dryness, and
inflammation.
Ingestion:
May cause irritation of the digestive tract. May cause central
nervous system depression, kidney damage, and liver damage. Symptoms
may include: headache, excitement, fatigue, nausea, vomiting,
stupor, and coma. May cause liver and kidney damage. May cause
central nervous system depression, characterized by excitement,
followed by headache, dizziness, drowsiness, and nausea. Advanced
stages may cause collapse, unconsciousness, coma and possible death
due to respiratory failure.
Inhalation:
Inhalation of high concentrations may cause central nervous system
effects characterized by nausea, headache, dizziness, unconsciousness
and coma. Causes respiratory tract irritation. May cause liver and
kidney damage. May cause motor incoordination and speech
abnormalities.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. Chronic
inhalation may cause effects similar to those of acute inhalation.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid
immediately.
Skin:
Flush skin with plenty of soap and water for at least 15 minutes
while removing contaminated clothing and shoes. Get medical aid if
irritation develops or persists. Wash clothing before reuse.
Ingestion:
Do NOT induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an
unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure to fresh air
immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical aid. Do NOT use
mouth-to-mouth resuscitation. If breathing has ceased apply
artificial respiration using oxygen and a suitable mechanical device
such as a bag and a mask.
Notes to Physician:
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
Containers can build up pressure if exposed to heat and/or fire. As
in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. During a
fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion. Use water spray to keep fire-exposed
containers csistant foam. For large fires, use water spray, fog, or
alcohol-resistant foam. Use water spray to cool fire-exposed
containers. Water may be ineffective. Do NOT use straight streams of
water. Cool containers with flooding quantities of water until well
after fire is out.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Avoid runoff into storm sewers and
ditches which lead to waterways. Wear appropriate protective clothing
to minimize contact with skin. Remove all sources of ignition.
Provide ventilation. A vapor suppressing foam may be used to reduce
vapors. Water spray may reduce vapor but may not prevent ignition in
closed spaces. Clean up residual material by washing area with a 2-5%
solution of soda ash.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use only in a well-ventilated area. Ground and
bond containers when transferring material. Avoid contact with eyes,
skin, and clothing. Empty containers retain product residue, (liquid
and/or vapor), and can be dangerous. Keep container tightly closed.
Avoid contact with heat, sparks and flame. Avoid ingestion and
inhalation. Do not pressurize, cut, weld, braze, solder, drill,
grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of
ignition. Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances.
Flammables-area.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits.
Personal Protective Equipment
Eyes:
Wear chemical goggles.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29CFR
1910.134 or European Standard EN 149. Always use a
NIOSH or European Standard EN 149 approved respirator
when necessary.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Appearance: clear, colorless
Odor: acetone-like
pH: Not available.
Vapor Pressure: 247 mbar @ 20 C
Vapor Density: 2.0 (Air=1)
Evaporation Rate: 7.7 (n-Butyl acetate=1)
Viscosity: 0.32 mPas 20 de
Boiling Point: 56 deg C @ 760mm Hg
Freezing/Melting Point: -94 deg C
Autoignition Temperature: 465 deg C ( 869.00 deg F)
Flash Point: -20 deg C ( -4.00 deg F)
Explosion Limits, lower: 2.50 vol %
Explosion Limits, upper: 12.8 vol %
Decomposition Temperature:
Solubility: soluble
Specific Gravity/Density: .7910g/cm3
Molecular Formula: C3H6O
Molecular Weight: 58.08
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable at room temperature in closed containers under normal storage
and handling conditions.
Conditions to Avoid:
High temperatures, ignition sources, temperatures above 220&C.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, perchlorates, aliphatic
amines, chromyl chloride, hexachloromelamine, chromic anhydride,
chloroform + alkali, potassium tert-butoxide.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon
dioxide.
Hazardest, rabbit, eye: 20 mg/24H
Moderate; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation,
mouse: LC50 = 44 gm/m3/4H; Inhalation, rat: LC50 = 50100 mg/m3/8H;
Oral, mouse: LD50 = 3 gm/kg; Oral, rabbit: LD50 = 5340 mg/kg; Oral,
rat: LD50 = 5800 mg/kg.
Carcinogenicity:
Acetone -
ACGIH: A4 - Not Classifiable as a Human Carcinogen
Epidemiology:
No information available.
Teratogenicity:
No information available.
Reproductive Effects:
TDLo(Oral, rat) = 273 gm/kg;Reproductive - Paternal Effects -
spermatogenesis (incl. genetic material, sperm morphology, motility,
and count).
Neurotoxicity:
No information available.
Mutagenicity:
Sex chromosome loss and nondisjunction(Yeast - Saccharomyces
cerevisiae) = 47600 ppm; Cytogenetic analysis(Rodent - hamster
Fibroblast)= 40 gm/L.
Other Studies:
Standard Draize Test: Administration onto the skin (human) = 500
mg/7days (Mild). Standard Draize Test: Administration onto the skin
(rabbit) = 500 mg/24H (Mild). Standard Draize Test( Eye, Rabbit) = 20
mg; Severe.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Material Safety Data Sheet Brown trout:Rainbow trout LC50=5540
mg/L/96H Sunfish (tap water), death at 14250 ppm/24H Mosquito fish
(turbid water) TLm=13000 ppm/48H Cas# 67-64-1: LC50 (96Hr.) rainbow
trout = 5540 mg/L; Static conditions, 11-13 degrees C LC50 (96Hr)
Fathead Minnow = 7280-8120 mg/L; Flow-through Conditions LC50 (96Hr)
Bluegill = 8300 mg/L
Other
For more information, see "HANDBOOK OF ENVIRONMENTAL FATE AND
EXPOSURE DATA."
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
US DOT
Shipping Name: ACETONE
Hazard Class: 3
UN Number: UN1090
Packing Group: II
Canadian TDG
Shipping Name: ACETONE
Hazard Class: 3
UN Number: UN1090
Other Information: FLASHPOINT -20 C
**** SECTION 15 - REGULATORY INFORMATION ****
US FEDERAL
TSCA
CAS# 67-64-1 is listed on the TSCA inventory.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous
Substances under the CWA.
None of the chemicals in this product are listed as Priority
Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants
under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous
by OSHA.
STATE
Acetone can be found on the following state right to know lists:
California, New Jersey, Florida, Pennsylvania, Minnesota,
Massachusetts.
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI F
Risk Phrases:
R 11 Highly flammable.
R 36 Irritating to eyes.
R 66 Repeated exposure may cause skin dryness or
cracking.
R 67 Vapors may cause drowsiness and dizziness.
Safety Phrases:
S 9 Keep container in a well-ventilated place.
S 16 Keep away from sources of ignition - No
smoking.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
WGK (Water Danger/Protection)
CAS# 67-64-1: 0
United Kingdom Occupational Exposure Limits
CAS# 67-64-1: OES-United Kingdom, TWA 750 ppm TWA; 1810 mg/m3 TWA
CAS# 67-64-1: OES-United Kingdom, STEL 1500 ppm STEL; 3620 mg/m3
STEL
Canada
CAS# 67-64-1 is listed on Canada's DSL List.
CAS# 67-64-1 is listed on Canada's Ingredient Disclosure List.
Exposure Limits
CAS# 67-64-1: OEL-AUSTRALIA:TWA 500 ppm (1185 mg/m3);STEL 100sp; OEL-FRANCE:TWA 750 ppm (1800 mg/m3)
OEL-GERMANY:TWA 1000 ppm (2400 mg/m3)
OEL-HUNGARY:TWA 600 mg/m3;STEL 1200 mg/m3
OEL-INDIA:TWA 750 ppm (1780 mg/m3);STEL 1000 ppm (2375 mg/m3)
OEL-JAPAN:TWA 200 ppm (470 mg/m3)
OEL-THE NETHERLANDS:TWA 750 ppm (1780 mg/m3) JAN9
OEL-THE PHILIPPINES:TWA 1000 ppm (2400 mg/m3)
OEL-POLAND:TWA 200 mg/m3
OEL-RUSSIA:TWA 200 ppm;STEL 200 mg/m3
OEL-SWEDEN:TWA 250 ppm (600 mg/m3);STEL 500 ppm (1200 mg/m3)
OEL-SWITZERLAND:TWA 750 ppm (1780 mg/m3)
OEL-TURKEY:TWA 1000 ppm (2400 mg/m3)
OEL-UNITED KINGDOM:TWA 750 ppm (1810 mg/m3);STEL 1250 ppm
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 7/27/1999 Revision #7 Date: 3/19/2001
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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